The Clinical Use of Tissue Adhesives: A Review of the Literature
Abstract
Sutures have traditionally been used in the emergency room and in the primary care setting for wound and laceration closure, but over the past several decades we have seen alternative methods of wound closure emerge. Tissue adhesives are starting to become the front-runner as the alternative to sutures. They possess many advantages and have shown great results when compared to sutures to include cost effectiveness, reduced infection rate, a reduced time requirement and improved cosmetic results. Over the past several years many other indications have started to emerge such as treatment for esophageal varices, application of skin grafts, and vascular embolization. The different chemical compositions and functions will also be reviewed. Disadvantages of tissue adhesives include lower tensile strength and a potential for systemic absorption or embolization. Overall, tissue adhesives provide an excellent means for wound closure in multiple settings and are the first choice method amongst clinicians across disciplines.
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Accepted 2014-03-05
Published 2014-03-05
